Transmission of Tuberculosis among Household Contacts of MDR-TB ab 79.9 € als Taschenbuch: MDR-TB Patients in Peninsular Malaysia. Aus dem Bereich: Bücher, Wissenschaft, Medizin,
Transmission of Tuberculosis among Household Contacts of MDR-TB ab 79.9 EURO MDR-TB Patients in Peninsular Malaysia
A Study identifying risk factors associated with development of MDR-TB, occurrence and pattern, morbidity and mortality of MDR-TB in Peninsular Malaysia is worthwhile. The genes such as MCP1, CCR2 and CD209 which might be associated with susceptibility or resistance to TB among household contacts of index cases would be highlighted in this study. This book contain two parts of studies, in Phase one was a retrospective study for epidemiology of Tuberculosis among household contacts of MDR-TB and risk factors associated with its developments. Phase two was a cross sectional study identifying the genetic variations analysis for three candidate genesof MCP-1, CCR2 and CD209 genes.
Treating tuberculosis (TB) remains a public health challenge in many developing countries. A retrospective cohort study was conducted on notified pulmonary TB cases in Kota Bharu district of Kelantan, Malaysia. Simple and multiple logistic regressions analysis were performed to identify factors associated with unsuccessful treatment outcomes.In univariable analysis, age, sex, educational level,employment status, family incomes as well as co-existence of extra-pulmonary TB, smoking, co-morbid diseases, HIV status, sputum cultures, chest X-ray findings and duration of delay were all found to have significant relationship with unsuccessful pulmonary TB treatment outcome. After adjusted for the confounders using multiple logistic regression analysis, the significant associated factors were age, positive HIV and advanced chest X-ray findings. This book discussed the associated factors for unsuccessful tuberculosis treatments which can guide the policy makers in the country to give more focus and priority among these high risks group of patients including strengthening the Directly Observed Treatment Short-course strategy.